Hematopoietic stem cells are adult stem cells in the blood system, a heterogeneous group with long-term self-renewal ability and the potential to differentiate into different types of mature blood cells.臍帶血 It is the longest and most intensively researched adult stem cell, and is of great significance in guiding the study of various types of stem cells, including tumor stem cells. Mature cells in the blood system have a very short lifespan, so hematopoietic stem cells need to replenish every mature cell in the blood system according to the body's physiological needs. At the same time, hematopoietic stem cells can also regulate and maintain the physiological balance of various components of the blood system under stressful conditions, such as injury or inflammation.

There are many cells in the human bloodstream, but they have a short life span and are dying all the time. New cells need to be produced to fill up these dying cells to maintain the normal function of our body,臍帶血 but how are these new cells produced? But how are these new cells produced? At this point, hematopoietic stem cells are produced. The cells in the blood keep dying and the hematopoietic stem cells keep producing new cells to fill them. This may not be intuitive enough. For example, you may understand it better here. The human body is like a steam locomotive running on rails. It is powered by the burning of coal, but coal burns very fast. If it is not replenished in time, the locomotive will not go far. New coal is needed to replenish it, but coal doesn't produce itself. A coal producer needs to keep adding new coal to the coal to keep the locomotive running, and the hematopoietic stem cells are the role of the coal producer, constantly producing new cells to fill the gap. If a worker goes on strike and stops working, or is lazy and fails to produce coal on time, the locomotive will not be able to maintain normal operation or stop. Similarly, in the human body, if the hematopoietic stem cells have a problem and cannot produce enough new cells to maintain the body's health, the body will develop a corresponding blood disorder.

Problems with hematopoietic stem cells can lead to tumors of the blood system (e.g., leukemia, lymphoma, myeloma, etc.) and other diseases of the blood system (e.g., primary immunodeficiency, aplastic anemia,臍帶血 spinal cord dysplasia, etc.). All of these diseases sound scary, but when the hematopoietic stem cells are at fault, the diseases they cause become even more complex and difficult to treat.

Hematopoietic stem cell transplantation is still very widely used, and is ideal for the treatment of blood and autoimmune diseases, as well as other solid tumors, especially in patients who have failed conventional therapy or who have relapsed and have poor prognostic factors, so the clinical use of hematopoietic stem cells is still relatively mature. So where do the hematopoietic stem cells come from if they are to be transplanted? We all know very well that it is stem cell donation, but I can't use it as long as I have stem cells, no matter who it is. This requires a match, and only those who are a match for you and have not been rejected can be used. After all, each locomotive has only one coal plant and is so proud of it. Therefore, it is necessary to constantly compare the matching samples in the bone marrow bank to find a suitable one, which is very similar to your own coal producer, preferably twins, so that the locomotive will accept this new coal producer and allow him to continue his previous work to maintain the normal operation of the locomotive.

At present, it is relatively difficult to find a suitable match for this type, and many affected patients do not wait for the similar coal producer until the last minute, which is very regrettable. Because stem cell donation is not yet a universal participation movement, which is only as a social welfare spontaneous learning behavior, not everyone is willing to donate, not everyone is suitable to donate, not to mention can not be guaranteed that all the company donation time can be in the most ideal treatment work time. This is where we need to improve our cord blood, which is the other main character of today's program.

Cord blood is the blood that remains in the placenta and umbilical cord after birth, when the umbilical cord is ligated and cut. Over the past decade, research has discovered that cord blood contains hematopoietic stem cells that can rebuild the body's hematopoietic and immune systems, and it can be used in bone marrow transplants to treat more than 80 diseases. As a result, cord blood has become an important source of hematopoietic stem cells, especially for unrelated hematopoietic stem cells. It is also a very important human biological resource. Take the example of former motorcycle and coal miners. A baby's cord blood, which is the most natural and uncontaminated, is stored at birth because it contains normal, healthy hematopoietic stem cells belonging to the baby's own coal miners, and the baby itself will not react adversely and does not need to be matched. In the long run, if a coal miner has a problem and is unable to function properly, a healthy coal miner (hematopoietic stem cells) can always be extracted from the cord blood and transplanted back into the body so that he or she can continue to work and stay healthy. Avoiding the waiting time of searching for a match in the bone marrow bank, the cord blood can be used at any time when the treatment needs to be extracted, in order to avoid delaying the treatment and to achieve the best treatment result.

Therefore, if finances allow, cord blood, umbilical cord, and placenta can be stored first, but one must not listen to exaggerated propaganda and blindly follow the trend, one must have the ability to judge. Storing umbilical cord blood is more likely to be a form of insurance and a form of psychological comfort.

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