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[Dunia]
COVID: 90% of patients treated with new Israeli drug discharged in 5 days
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https://www.jpost.com/health-science/covid-90-percent-of-patients-treated-with-new-israeli-drug-discharged-in-5-days-675961
COVID: 90% of patients treated with new Israeli drug discharged in 5 daysThe Phase II trial for an Israeli COVID drug saw some 29 out of 30 patients, moderate to serious, recover within days.
Some 93% of 90 coronavirus serious patients treated in several Greek hospitals with a new drug developed by a team at Tel Aviv’s Sourasky Medical Center as part of the Phase II trial of the treatment were discharged in five days or fewer.
The Phase II trial confirmed the results of Phase I, which was conducted in Israel last winter and saw 29 out of 30 patients in moderate to serious condition recover within days.
“The main goal of this study was to verify that the drug is safe,” Prof. Nadir Arber said. “To this day we have not registered any significant side effect in any patient from both groups.”
The trial was conducted in Athens because Israel did not have enough relevant patients. The principal investigator was Greece’s coronavirus commissioner, Prof. Sotiris Tsiodras.
Arber and his team, including Dr. Shiran Shapira, developed the drug based on a molecule that the professor has been studying for 25 years called CD24, which is naturally present in the body.
“It is important to remember that 19 out of 20 COVID-19 patients do not need any therapy,” Arber said. “After a window of five to 12 days, some 5% of the patients start to deteriorate.”
The main cause of the clinical deterioration is an over activation of the immune system, also known as a cytokine storm. In case of COVID-19 patients, the system starts attacking healthy cells in the lungs.
“This is exactly the problem that our drug targets,” he said.
CD24 is a small protein that is anchored to the membrane of the cells and it serves many functions including regulating the mechanism responsible for the cytokine storm.
Arber stressed that their treatment, EXO-CD24, does not affect the immune system as a whole, but only targets this specific mechanism, helping find again its correct balance.
“This is precision medicine,” he said. “We are very happy that we have found a tool to tackle the physiology of the disease.”
“Steroids for example shut down the entire immune system,” he further explained. “We are balancing the part responsible for the cytokine storms using the endogenous mechanism of the body, meaning tools offered by the body itself.”
Arber noted that another breakthrough element of this treatment is its delivery.
“We are employing exosomes, very small vesicles derived from the membrane of the cells which are responsible for the exchange of information between them,” he said.
“By managing to deliver them exactly where they are needed, we avoid many side effects,” he added.
The team is now ready to launch the last phase of the study.
“As promising as the findings of the first phases of a treatment can be, no one can be sure of anything until results are compared to the ones of patients who receive a placebo,” he said.
Some 155 coronavirus patients will take part in the study. Two-thirds of them will be administered the drug, and one-third a placebo.
The study will be conducted in Israel and it might be also carried out in other places if the number of patients in the country will not suffice.
“We hope to complete it by the end of the year,” Arber said.
If the results are confirmed, he vowed that the treatment can be made available relatively quickly and at a low cost.
“In addition, a success could pave the wave to treat many other diseases,” he concluded.
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SOALAN:
Kalau ubat ini betul2 berkesan, boleh ke kita orang2 Islam guna ?
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boleh ja guna, nak tunggu invention ummat melayu sampai 10 juta tahun lagi pon tak muncul2, baik guna produk yahudi laknatulloh
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kalau ada pengedar dan pengeluar bukan dari israel lah. selagi pengedar or kilang di israel. xleh masuk malaysia.
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mana boleh guna ubat...bukan ke ada vaksin maa...ubat tu belum di uji cuba lagi... |
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ChildrenOfBodom replied at 10-8-2021 01:26 PM
boleh ja guna, nak tunggu invention ummat melayu sampai 10 juta tahun lagi pon tak muncul2, baik g ...
Haha.. org kita kalut tang poligami nk cari point nk tambah bini while also kalut tang aurat perempuan.
Hal2 lain bg puak2 yahudi nasrani yg setel n kita menadah aje sambil kutuk2 yahudi nasoro cemburu dgn kejayaan ummah. |
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natang ni terang2 kat botoi dia made in israel, kat malaysia bersepah ada juai. online pon berlambak..rasa berlambak lagi kot ubat2 made in israel ada dalam pasaran malaysia
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xnampak pun perkataan israel dekat gambar tu
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Nanti bila WHO kata selamat dan berksan, DG Hisyam cina advice kat gomen suruh guna produk israel yg ternyata berkesan tu, mahiaddin bgtaw kat menteri ugama suh kuaq fatwa dibolehkan guna produk ni, settle la masalah dan kegusaran ummah. |
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wow. macam mana boleh terlepas. Lobai PAS xperasan ke ada produk ni di pasaran?
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ChildrenOfBodom replied at 10-8-2021 01:35 PM
natang ni terang2 kat botoi dia made in israel, kat malaysia bersepah ada juai. online pon berlamb ...
Kalau mengikut fatwa...barang atau buatan yahuds kita boleh makan...tapi yg kita ditegah...jgn tidur dirumah mereka....
Kau pernah dengar kewww COB? |
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tah2 lobai PAS pon guna nak bagi janggut panjang
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makan rumah orang yahudi tdoq di rumah orang nasroni.. penah dengaq nii
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jenuh lepas ni malaysia kena troll dekat twitter zionist ni guna ubat depa |
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ChildrenOfBodom replied at 10-8-2021 01:44 PM
makan rumah orang yahudi tdoq di rumah orang nasroni.. penah dengaq nii
kita tunggu pakar fatwa @mbhcsf kita mencemar duli utk verify khen....
Roger |
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nenekglamer replied at 10-8-2021 01:35 PM
Haha.. org kita kalut tang poligami nk cari point nk tambah bini while also kalut tang aurat perem ...
Setuju 1000% . Basic sains pon malas nk faham n bengap jugak, lg nk keluarkan produk. Jd agent promote dajal jah boleh. Xhabis2 dajal kehulu kehilir |
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stingerlympics replied at 10-8-2021 01:42 PM
Kalau mengikut fatwa...barang atau buatan yahuds kita boleh makan...tapi yg kita ditegah...jgn tid ...
I baru nk ckp pasal ni. Kalau tmpt tu x ada makanan halal @ ragu halal boleh mintak kosher food kan? Sbb yahudi ortodok mmg ikut kitab2 lama |
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totokreturn. replied at 10-8-2021 01:44 PM
jenuh lepas ni malaysia kena troll dekat twitter zionist ni guna ubat depa
Yg kaki troll tu mesti budak2 kuat ponteng sekolah, masa sekolah kelas belakang. Memalukan malaysia. Bodoh nak mampos. Troll yahudi, lepas tu org malaysia bergaduh sana sni isu palestin. Tgk sudan dgn negara apa tu diam2, tp tolak israel di peringkat antarabangsa. Peserta malaysia belum tentu mampu buat mcm tu. Kalau mampu, belum tentu kalis kutukan puak kaki troll |
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Tah2 Yisrael pun tanak bagi sapa suh hencap depa kat socmed katanyaa
Di booo nye ummah sini, lama gak depa koyak ngn malaysia.
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Post time 10-8-2021 01:13 PM
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