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Author: lurkingaround

[Tempatan] Ada risiko jangka panjang mRNA Covid-19 vaksin.?

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Post time 4-12-2021 10:40 AM From the mobile phone | Show all posts
shy79 replied at 3-12-2021 05:34 PM
ok yg ni baru i phm..beza dr segi structural molecular nya
orait tq for info
sat lagi baru nk gug ...

https://www.theedgemarkets.com/article/no-mixing-booster-shots-pfizer-recipients-decision-astrazeneca-soon-says-khairy

Sis, minta maaf iols baru jumpa info yang booster Pfizer ni homolog kepada dos 1 dan 2 Pfizer

DOS KETIGA PFIZER ni penerima dos 1 dan 2 Pfizer je dapat.
So Dos 1, 2 dan 3 Pfizer semua homolog. Struktur sama, sumber yang sama
Ambil lepas 6 bulan dos ke-2

Booster Pfizer ni utk org yg amik dos 1 dan 2 vaksin lain. Rasanya dua2 tu Comirnaty benda yang sama
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Post time 4-12-2021 01:26 PM From the mobile phone | Show all posts
Edited by Dwdrum at 3-12-2021 09:28 PM
KIM.K replied at 2-12-2021 05:15 PM
Gini la sis
Dia macam u kata saya expert buat sandwich
Expertise u sandwich, bukan buat roti


Tidak perlu butthurt sis... Aku tahu none in malaysia expert mrna.... Crispr dan lipid less than   5 years di malaysia.... Bukan expertise ko kim
  i tidak perlu mentioned 1 name uni di malaysia ada  buat workshop. Crispr ssmua masih merangkak... Aku tahu... Mahu experti perlu pandai tools no tools semua bullshit saja... Tool vuna untuk study
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Post time 4-12-2021 01:33 PM From the mobile phone | Show all posts
KIM.K replied at 2-12-2021 05:30 PM
lipid nanoparticle-formulated mRNA vaccines coding for the SARS-CoV-2 full-length spike protein ha ...

Pernah denvar siRNA?
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Post time 4-12-2021 01:38 PM From the mobile phone | Show all posts
Dwdrum replied at 4-12-2021 01:26 PM
Tidak perlu butthurt sis... Aku tahu none in malaysia expert mrna.... Crispr dan lipid less than   ...

Aku pun tak pernah jumpa any lecturer in med school tak reti signaling ni. Regardless diorg buat paper apa pun sangat fasih.
Nak kena maki dgn dekan tak reti baca paper

Maybe org membaca paper tapi tak biasa motor skills buat experiments
Kalau prof i dulu jadi abdi kat proteomic and gene expression labs
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Post time 4-12-2021 01:48 PM From the mobile phone | Show all posts
KIM.K replied at 3-12-2021 09:38 PM
Aku pun tak pernah jumpa any lecturer in med school tak reti signaling ni. Regardless diorg buat p ...

Bukan semua DR itu Scientist ramai juga benak dalam scientific study...tidak ramai physician really involved bidang scientific.... Med grad masuk dalam research di awal depa semua merangkak.. Scientific setting berbeza... Sebab itu di tempat i ramai dr sambung phd subfield study lain grad dari faculty lain seperti math.. Physics. Engineering etc.... Tanya Dr depa reti guna phyton?.. Paling busuk pun matlab.....
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Post time 4-12-2021 01:54 PM From the mobile phone | Show all posts
Dwdrum replied at 4-12-2021 01:33 PM
Pernah denvar siRNA?

Silencing rna. U buat ke?

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Post time 4-12-2021 01:57 PM From the mobile phone | Show all posts
Dwdrum replied at 4-12-2021 01:48 PM
Bukan semua DR itu Scientist ramai juga benak dalam scientific study...tidak ramai physician reall ...

Thats why i kata org tulis paper, present, termengah2 kat lab dia tau la selok belok bidang dia
Yang taktau tu nganga
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Post time 5-12-2021 12:37 PM From the mobile phone | Show all posts
https://www.who.int/news/item/28-11-2021-update-on-omicron

Covid treatment sekarang pakai IL-6 receptor blocker pasal nak stop inflammatory marker. Nilah sebabnya org belajar signaling nak blok certain enzyme from producing deleterious proteins
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 Author| Post time 5-12-2021 04:17 PM | Show all posts
KIM.K replied at 5-12-2021 12:37 PM
https://www.who.int/news/item/28-11-2021-update-on-omicron

Covid treatment sekarang pakai IL-6 rece ...

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WHO sudah cadang IL-6 receptor blockers sejak Julai 2021 tapi masih ramai mati Covid selepas itu, sama spt cadangan tahun dulu untuk corticosteroid, iaitu dexamethasone. .......

https://www.who.int/news/item/06 ... dly-increase-access - 06-07-2021 - WHO recommends-life-saving-interleukin-6-receptor-blockers-for-covid-19-and-urges-producers-to-join-efforts-to-rapidly-increase-access
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Buta2 menghindari reaksi keradangan/"inflammation" dari pesakit2 Covid mungkin telah buat keadaan mereka lebih buruk........

https://kids.frontiersin.org/articles/10.3389/frym.2018.00051 - May Inflammation Be With You! / Semoga Keradangan Bersama Anda! - 21 Sep 2018
Abstract

Inflammation is a protective reaction of the body against injury or infection, in which the affected area becomes swollen, hot, red, and painful. In the past, it was believed that this reaction was dangerous and that anti-inflammatory medicines were necessary. However, we now recognize inflammation as a protective and necessary response of our internal defense system, and we know that it may not always be good to block it. ...

abstrak

Keradangan adalah tindak balas perlindungan badan terhadap kecederaan atau jangkitan, di mana kawasan yang terjejas menjadi bengkak, panas, merah, dan menyakitkan. Pada masa lalu, adalah dipercayai bahawa tindak balas ini berbahaya dan ubat anti-radang diperlukan. Walau bagaimanapun, kami kini mengiktiraf keradangan sebagai tindak balas perlindungan dan perlu bagi sistem pertahanan dalaman kami, dan kami tahu bahawa ia mungkin tidak selalu baik untuk menyekatnya. ...

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Post time 6-12-2021 02:26 PM From the mobile phone | Show all posts
Edited by KIM.K at 6-12-2021 02:42 PM
lurkingaround replied at 5-12-2021 04:17 PM
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WHO sudah cadang IL-6 receptor blockers sejak Julai 2021 tapi masih ramai mati Covid selepas itu ...


https://www.frontiersin.org/articles/10.3389/fimmu.2021.683800/full

IL6 activation ni downstream daripada pengumpulan ANG II dalam serum. ANG II sepatutnya dipotong oleh ACE2 tapi ACE2 bind SARS-COV-2. Ini menyebabkan inflammation akibat overexpression ANG II

https://www.ahajournals.org/doi/full/10.1161/01.HYP.0000248135.97380.76

ANG II aktifkan IL-6 proinflammatory marker. Isi tersirat: IL-6 downstream pathway kepada ANG II, punca inflammation
Apabila blok IL-6, overexpression ANG II masih berlaku maka keradangan berterusan. Jadi mengapa blok downstream protein?

Most paper mencadangkan blok ANG I atau di punca SARS-COV-2/ACE II binding site.
ANG I hydrolisis oleh mangkin ACE jadi ANG II.

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Post time 6-12-2021 03:58 PM From the mobile phone | Show all posts
Edited by KIM.K at 6-12-2021 05:46 PM

Aku terbaca kenyataan sorang konspirator antivaksin ni dia mention, blood clotting leads to higher concentration of blood plasma

Boleh sesapa tolong explain
Plasma protein ke, fibrinogen ke. Apa maksud kena strok, trombosis menyebabkan plasma tinggi dalam darah pesakit

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Post time 6-12-2021 05:48 PM From the mobile phone | Show all posts
Edited by KIM.K at 6-12-2021 05:50 PM

https://www.healthline.com/health/thick-blood

Blood clotting disorders that cause thick blood tend to be rare. Some of the more common include factor V Leiden, which an estimated 3 to 7 percent of the general population has. This condition doesn’t mean a person’s blood will be too thick, but that they are predisposed to having thick blood.

Of all the people who’ve had a blood clot in their veins, less than 15 percent are due to a condition that causes thick blood

What are the symptoms of thick blood?
Many don’t have any symptoms of thick blood until they experience a blood clot. The blood clot usually occurs in a person’s vein, which can cause pain and affect circulation in and around the area where the clot occurs.

Some are aware they have a family history of a blood clotting disorder. This may motivate them to be tested for blood clotting issues before any arise.
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Post time 6-12-2021 05:59 PM From the mobile phone | Show all posts
https://www.cancersmoc.com/blood-thickness/

Thick blood is caused by heavy proteins, or by too much blood in the circulation. Too many red cells, white cells, and platelets will result in blood thickening. Another cause is an imbalance in the blood clotting system. Specific diseases include lupus, inhibitors, deficiency in protein C or S or antithrombin, or mutations in Factor 5 or prothrombin. Cancer can also cause blood thickening.

Sebenarnya, pemekatan plasma darah yang menyebabkan darah beku. Bukan darah beku menyebabkan pemekatan plasma

Bagi seseorang yang gopoh, tamak dan terlalu nak membongak, tak layak panggil gifted and highly knowledgeable researcher as menipu safety protocols. Safety protocols in business ni aku tulis SOP keselamatan dua tahun sebelum jadi undang-undang import export dangerous goods di malaysia ni.
IQ kena depan sebelum masa.
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Post time 6-12-2021 06:01 PM From the mobile phone | Show all posts
Edited by KIM.K at 6-12-2021 06:03 PM

Kaki konspirashit forum sebelum nak bukak mulut kat fb tu, study elok2 la. Jangan nak humblebrag semata. Kalau IQ ko tinggi takpe

Aku nak tanya apsal orang dah amik 2 jab baru kau nak ajar konspirasi kenapa ko sekeluarga tak amik jab pastu kau boleh plak jual penawar?

Ko ingat IQ kitorang level2 family kau ke? Segala mala anak beranak follower kau dah kiok, baru nak cerita kau antivak terpaling? Nak kena penampor jepun?
Berani lak jual ubat penawar baksin
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Post time 6-12-2021 06:06 PM From the mobile phone | Show all posts
Orang dah amik jab kau pun launch ubat penawar baksin. Kau pun sama level takguna dengan aluminium tuhhh...muntah baca dakwah dalam gelap gini
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 Author| Post time 6-12-2021 06:29 PM | Show all posts
Edited by lurkingaround at 6-12-2021 06:36 PM
KIM.K replied at 6-12-2021 03:58 PM
Aku terbaca kenyataan sorang konspirator antivaksin ni dia mention, blood clotting leads to higher c ...

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Persoalannya bertumpu kepada kesan sampingan gumpalan darah/"blood clots" dari vaksin Covid AstraZeneca. Jumlah yang mati akibatnya adalah kecil tapi terbukti ada risiko. Telah lengkap vaksin AZ, ramai orang2 UK pun mati Covid = macam tak berapa berkesan untuk menyelamat nyawa segelintir orang spt orang2 tua berpenyakit/"comorbid". .......

https://www.bbc.com/news/health-59418123 - Covid: Trigger of rare blood clots with AstraZeneca jab found by scientists / Covid: Pencetus gumpalan darah yang jarang-ditemui dengan AstraZeneca Jab, dijumpai oleh saintis - 2 Dec 2021

Patutkah Rakyat ambil risiko gumpalan darah/"blood clot" dari vaksin Covid AZ walaupun risiko mati adalah kecil.? Bagaimana pula kalau risiko kecederaan dari gumpalan darah/"blood clots" ini yang risikonya mungkin lebih tinggi.? ... Vaksin Covid Sinovac hampir tiada risiko gumpalan darah/"blood clots" ini, iaitu tiada risiko mati atau cedera.
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Post time 6-12-2021 09:49 PM From the mobile phone | Show all posts
lurkingaround replied at 6-12-2021 06:29 PM
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Persoalannya bertumpu kepada kesan sampingan gumpalan darah/"blood clots" dari vaksin Covid Astra ...

Ko ni KBAT fail, saja aku malas nak highlight

Bila masa persoalannya blood clot disebabkan AZ. Konspirator terpaling antivak ni tak sebut AZ, maybe dah terkenal side effect AZ. Itu hanya quick generalization, WHO report Sinopharm ada kes thrombus. Aku tegur sebab doesnt sound quite right

Comorbids sebaiknya tak amik AZ atas self awareness. Takda profesional berani suggest, aku lagi tak boleh. AZ menafikan tuduhan blood clots so you're on your own

https://www.medicalnewstoday.com/articles/sinopharm-covid-19-vaccine-should-you-worry-about-the-side-effects#Serious-side-effects

Ko dah tau IL-6 receptor blocker tu useless dan ramai terkorban, gi la cari the big why. Tu pasal aku jumpa IL-6 ni downstream cytokine. Jangan kais2 permukaan je, gi gali deeper cognitive resolutions. Molecular answer to the medical cause. One answer at a time

Aku pun belum kupas mekanisma vaksin setakat ni. Baru sentuh virus
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 Author| Post time 6-12-2021 11:17 PM | Show all posts
KIM.K replied at 6-12-2021 09:49 PM
Ko ni KBAT fail, saja aku malas nak highlight

Bila masa persoalannya blood clot disebabkan AZ. K ...
... WHO report Sinopharm ada kes thrombus. ....

.
Sila beri sumber berita itu.
.


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Post time 6-12-2021 11:27 PM From the mobile phone | Show all posts
lurkingaround replied at 6-12-2021 11:17 PM
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Sila beri sumber berita itu.
.

Skroll link tu
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 Author| Post time 6-12-2021 11:57 PM | Show all posts
Edited by lurkingaround at 7-12-2021 03:03 PM

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https://www.medicalnewstoday.com ... erious-side-effects
Serious side effects
The WHO identified two serious adverse events that were possibly linked to the vaccine — serious nausea and a rare neurological disorder known as acute disseminated encephalomyelitis. There was also one diagnosis of thrombus (blood clot) in the vaccine group.
The WHO also considered post-authorization data in the form of safety data gathered during China’s rollout of the vaccine. Among the 5.9 million people who had received the vaccine in China by December 30, 2020, there were 1,453 reported adverse events.
These side effects included local reactions of redness and swelling at the vaccination site. There were also 202 cases of fever, including 86 classed as severe. Although there were 11 reported cases of facial nerve symptoms, assessors concluded that these were unrelated to the vaccine.

Kesan sampingan yang serius
WHO mengenal pasti dua kejadian buruk yang serius yang mungkin dikaitkan dengan vaksin - loya yang serius dan gangguan neurologi yang jarang dikenali sebagai ensefalomyelitis disebarkan akut. Terdapat juga satu diagnosis trombus (bekuan darah) dalam kumpulan vaksin.

WHO juga mempertimbangkan data pasca kebenaran dalam bentuk data keselamatan yang dikumpul semasa pelancaran vaksin China. Antara 5.9 juta orang yang telah menerima vaksin di China pada 30 Disember 2020, terdapat 1,453 kejadian buruk yang dilaporkan.

Kesan sampingan ini termasuk reaksi tempatan kemerahan dan bengkak di tapak vaksinasi. Terdapat juga 202 kes demam, termasuk 86 dikelaskan sebagai teruk. Walaupun terdapat 11 kes gejala saraf muka yang dilaporkan, penilai membuat kesimpulan bahawa ini tidak berkaitan dengan vaksin.

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Satu kes (dari 661 "test subjects") trombus itu mungkin dikaitkan dengan vaksin Sinopharm dalam trialnya dan tiada satu kes trombus pun bila vaksin Sinopharm diberi kepada 5.9 juta orang di Cina pada 30 Dis 2020.
.

https://www.e-cep.org/journal/view.php?number=20125555451 - Thrombosis and severe acute respiratory syndrome coronavirus 2 vaccines: vaccine-induced immune thrombotic thrombocytopenia - 30 June 2021
Dalam kertas kajian ini, kebanyakkan kes kesan sampingan serius trombosis berlaku dengan vaksin AZ = tiada dengan vaksin Sinopharm.

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